Liver Resection Under Ischemia: Inflow Occlusion or Total Hepatic Isolation
نویسنده
چکیده
203 surgery group. The procedure-related complications (28% and 32%, respectively) and 30 day mortality (8% and 20%) were similar. Although the initial hospital stay was significantly shorter in the stented group (18 vs 24 days), this difference was not maintained when readmissions for obstructed endoprostheses and duodenal obstruction were also considered. Another study by Dowsett et al. included 127 patients with unresectable malignancy obstructing the distalbile duct2. Sixty-five patients were treated via endoscopic stenting and 62 had surgical palliation. Successful biliary drainage was achieved in 94% of patients, with the 30 day mortality being 6% after endoscopy and 15% after surgery. However, recurrent jaundice (17% vs 3%) and late duodenal obstruction (14% vs 3%) were seen more commonly in the endoprosthesis group. Unfortunately, no prospective randomized studies have compared surgical to nonsurgical palliation ofhilar cholanginocarcinoma or more proximal biliary obstruction , and therefore data applicable to this situation are lacking. In conclusion, the management of patients with obstructive jaundice from either benign or malignant processes no longer resides solely within the hands of surgeons. A multidisciplinary approach to such a problems is currently indicated, with some patients being best treated by endoscopic or percutaneous techniques, others by surgical techniques, and still others using a multidisciplinary approach. Operatively placed transhepatic stents continue to play an important role in the management of these patients. So do the procedures performed by our talented endoscopists and interven-tional radiologists. The role of U tube palliative treatment in high bile duct carcinoma. duct tumors. Surgical management with silastic transhepatic biliary stents. (1992) Transhepatic biliary stents in high benign and malignant biliary tract obstructions. In: Mechanisms of major biliary injury during laparoscopic cholecystectomy. Spectrum and management of major complications of laparoscopic cholecystectomy. Am. Treatment of proximal biliary tract carcinoma: An overview of techniques and results. Surgery, 97, 251-262. (1990) Management of proximal cholangiocarcinomas by surgical resection and radiotherapy. Am. Randomized trial of self-expanding metal stents versus polyethylene stents for distal malignant biliary obstruction. Prospective controlled trial of transhepatic biliary endopros-thesis versus bypass surgery for incurable carcinoma of the head of the pancreas. Lancet, 1, 69-71. Malignant obstructive jaundice: A prospective randomized trial of bypass surgery versus endoscopic stenting. Gastro-enterology, 96, A 128.
منابع مشابه
Vascular occlusion techniques during liver resection.
Control of bleeding from the transected liver basically consists of vascular inflow occlusion and control of hepatic venous backflow from the caval vein. Central venous pressure determines the pressure in the hepatic veins and is an extremely important factor in controlling blood loss through venous backflow. Vascular inflow occlusion (Pringle maneuver) involves clamping of the portal vein and ...
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OBJECTIVE To evaluate the protective effects of ischemic preconditioning in a prospective randomized study involving a large population of unselected patients and to identify factors affecting the protective effects. SUMMARY BACKGROUND DATA Ischemic preconditioning is an effective protective strategy in several animal models. Protection has also been suggested in a small series of patients un...
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BACKGROUND Historically, the primary hazard with liver surgery has been intraoperative blood loss. This led to the refinement of inflow and outflow occlusive techniques. The utility of the different methods of inflow and outflow techniques for hepatic surgery were reviewed. METHODS A search of the English literature (Medline, Embase, Cochrane library, Cochrane clinical trials registry, hand s...
متن کاملLiver Resection Under Inflow Occlusion: A Bloodless Operation?
Aortic occlusion and vascular isolation allowing avascular hepatic resection. Archives of Occlusion of the supracellac abdominal aorta and hepatic vascular isolation were employed in a series of 15 patients as a definitive method to allow avascular hepatic re-section. The series was compared with an earlier group of patients treated conventionally. In the avascular hepatic resection group there...
متن کاملIschemic preconditioning improves postoperative outcome after liver resections: a randomized controlled study.
BACKGROUND Clamping of the portal triad (Pringle maneuver) prevents blood loss during liver resection, but leads to liver injury upon reperfusion. Ischemic preconditioning (IP) has been shown to protect the liver against prolonged ischemic injury in animal models. However, the clinical value of this procedure has not yet been established. METHODS 61 Patients undergoing hepatic resection under...
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OBJECTIVES The intermittent Pringle maneuver (IPM) is frequently applied to minimize blood loss during liver transection. Clamping the hepatoduodenal ligament blocks the hepatic inflow, which leads to a non circulating (hepato)splanchnic outflow. Also, IPM blocks the mesenteric venous drainage (as well as the splenic drainage) with raising pressure in the microvascular network of the intestinal...
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ورودعنوان ژورنال:
- HPB Surgery
دوره 8 شماره
صفحات -
تاریخ انتشار 1995